A procedure for the preparation and isolation of nucleoside-5’-diphosphates

نویسندگان

  • Heidi J Korhonen
  • Hannah L Bolt
  • David R W Hodgson
چکیده

Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5'-tosylnucleosides to afford nucleoside-5'-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5'-diphosphates from crude reaction mixtures.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2015